EKPONG, BASSEY OGON

Recent Microbiology Graduate & Computational Research Specialist
Calabar, NG.

About

Highly motivated and detail-oriented recent Microbiology graduate with a Second Class Upper Division, specializing in computational and experimental research for drug discovery and antimicrobial activity. Proven ability to apply advanced simulation tools, molecular techniques, and laboratory procedures to drive impactful scientific investigations and contribute to pharmaceutical advancements. Eager to leverage strong analytical and technical skills in a challenging research or laboratory role.

Work

Computational and Bio-Simulation Research Group, University of Calabar
|

Graduate Research Assistant

Calabar, Cross River State, Nigeria

Summary

Led computational and simulation projects focused on drug delivery research and biosensor design, leveraging advanced molecular modeling and pharmacokinetic analysis.

Highlights

Spearheaded the application of advanced computational and simulation tools to accelerate drug delivery research, identifying novel therapeutic pathways and optimizing compound efficacy.

Pioneered investigations into nanomaterial applications for biosensor design and drug delivery systems, contributing to advancements in diagnostic capabilities and targeted therapy.

Executed complex ligand molecule modeling for pharmaceutical applications using DFT, Gaussian 16, Biovia Discovery Studio, Autodock Vina, Pyrx, and PYMOL, informing drug candidate selection and optimization.

Leveraged online web servers for comprehensive pharmacokinetic (ADMET) analysis of ligand molecules, optimizing drug candidate profiles for efficacy, safety, and bioavailability.

New Age International Secondary School Omata
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Teaching Assistant (NYSC)

Omata, Ebonyi State, Nigeria

Summary

Instructed senior school students in Biology and Chemistry, fostering academic growth and scientific understanding.

Highlights

Delivered engaging and comprehensive lessons in Biology and Chemistry to senior school students, enhancing understanding of complex scientific concepts.

Supported student learning through individualized instruction and group activities, contributing to improved academic performance and scientific literacy.

Developed and implemented effective teaching strategies tailored to diverse learning styles, promoting an inclusive and dynamic classroom environment.

Department of Microbiology, University of Calabar
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Undergraduate Researcher

Calabar, Cross River State, Nigeria

Summary

Conducted experimental and computational studies on isoflavanol extraction, antimicrobial activity, and molecular interactions, contributing to thesis research.

Highlights

Successfully extracted and characterized isoflavanol from Nigerian propolis using both experimental and computational methods, establishing a foundation for antimicrobial drug development.

Performed agar well diffusion assays to determine antimicrobial activity against Methicillin-resistant Staphylococcus aureus, E. coli, H. pylori, C. albicans, and C. tropicalis, identifying potential therapeutic agents.

Executed computational characterization of the electronic properties of isoflavanol structures, providing insights into their reactivity and potential mechanisms of action.

Conducted molecular docking of isoflavanol against key microbial proteins, elucidating binding affinities and predicting potential drug targets for novel antimicrobial therapies.

Analyzed the pharmacokinetics of isoflavonol, assessing its absorption, distribution, metabolism, and excretion properties to predict in-vivo behavior and optimize drug design.

Winas Medical Laboratory and Diagnostic Center
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Laboratory Assistant

Calabar, Cross River State, Nigeria

Summary

Managed laboratory samples, performed quality control, assisted in diagnostic procedures, and trained new personnel to ensure operational excellence.

Highlights

Streamlined sample identification, collection, and handling processes, significantly improving laboratory efficiency and data integrity.

Conducted rigorous quality control tests on all laboratory results, ensuring 100% accuracy and reliability of diagnostic outcomes.

Assisted in a wide range of medical laboratory procedures, including sample analysis, serological, hematological, and microbial diagnostics, supporting accurate patient diagnoses.

Provided comprehensive training and mentorship to new laboratory trainees in microbiological procedures, enhancing team capabilities and adherence to safety protocols.

Winas Medical Laboratory and Diagnostic Center
|

Industrial Trainee

Calabar, Cross River State, Nigeria

Summary

Gained hands-on experience in medical laboratory procedures, supporting diagnostic processes and operational workflows.

Highlights

Assisted in medical laboratory procedures, including sample analysis, serological, hematological, and microbial diagnostics, gaining practical expertise in clinical testing.

Contributed to efficient laboratory operations by supporting sample preparation and data entry, ensuring timely processing of diagnostic tests.

Learned and applied best practices in laboratory safety and quality control, maintaining high standards for accuracy and compliance.

Volunteer

NYSC
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Community Development Service

Summary

Conducted community awareness campaigns on drug usage and abuse prevention.

Highlights

Orchestrated community awareness and sensitization campaigns focused on drug usage and abuse, educating residents on prevention and risks.

Engaged community members through interactive sessions and materials, fostering informed decision-making regarding substance abuse.

World Health Organization
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Enhanced Independent Monitoring

Ebonyi State, Nigeria

Summary

Monitored nOPV2 vaccination processes and ensured high vaccination rates in rural communities.

Highlights

Monitored the nOPV2 vaccination process in rural communities across Ebonyi State, ensuring adherence to public health protocols.

Ensured that all eligible children under 5 years old were vaccinated against polio, contributing to critical public health outcomes.

Delivered daily presentations on vaccination outcomes for visited communities, facilitating transparent communication and accountability.

Community Development Service (CDS) National Youth Service Corp (NYSC) Onicha L.G.A
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President

Onicha L.G.A, Ebonyi State, Nigeria

Summary

Led the Community Development Service initiatives for the National Youth Service Corp, overseeing program execution and member engagement.

Highlights

Presided over the CDS group, directing strategic planning and implementation of community development projects within Onicha L.G.A.

Mobilized and managed Corp members for various community initiatives, ensuring effective resource allocation and project delivery.

Represented the CDS group in liaisons with local authorities and stakeholders, fostering collaborative partnerships for community upliftment.

OCI Foundation
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Cancer Prevention Campaign

Summary

Promoted awareness and education on breast and cervical cancer screening and treatment.

Highlights

Promoted breast and cervical cancer screening and treatment awareness through targeted campaigns, reaching diverse community demographics.

Educated the public on early detection methods and available treatment options, contributing to improved health outcomes.

NYSC
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Disease Awareness and Control Campaign

Summary

Led a three-week campaign on Hepatitis B, Lassa fever, and Cholera for Corp members.

Highlights

Led a three-week awareness, surveillance, and control campaign on Hepatitis B, Lassa fever, and Cholera for Corp members, enhancing public health knowledge.

Provided critical information on disease prevention, symptoms, and management strategies, empowering participants to safeguard their health.

Yala-Obubra Students Association (YOSA)
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Chief Press Secretary to the President

Summary

Handled public relations and communication strategies for the Yala-Obubra Students Association, enhancing visibility and member outreach.

Highlights

Drafted and disseminated press releases, official statements, and promotional materials, effectively communicating YOSA's mission and activities.

Managed media relations and public image, ensuring positive representation of the association to stakeholders and the wider community.

Developed engaging content for internal and external communications, fostering strong connections with members and partners.

Nigerian Association of Microbiology Students, University of Calabar (NAMS-UCC)
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General Secretary

Calabar, Cross River State, Nigeria

Summary

Managed administrative and communication functions for the Microbiology Students Association, supporting student engagement and academic activities.

Highlights

Managed all official correspondence and records for NAMS-UCC, ensuring efficient communication and organizational transparency.

Coordinated logistics for student meetings, events, and academic programs, facilitating active participation and engagement.

Supported the executive board in strategic planning and decision-making, contributing to the overall success of student initiatives.

Catholic Alter Servers Association, Christ the King Station Num-Yala, St. Francis Xavier Parish Obubra
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General Secretary

Num-Yala, Cross River State, Nigeria

Summary

Maintained records and facilitated communication for the Catholic Alter Servers Association, supporting liturgical and organizational functions.

Highlights

Maintained accurate records of meetings, membership, and activities for the association, ensuring clear historical documentation.

Facilitated internal and external communications, ensuring timely dissemination of information to members and parish leadership.

Supported the President in administrative tasks and event coordination, contributing to the smooth operation of the association.

Education

University of Calabar
Calabar, Cross River State, Nigeria

BSc

Microbiology

Grade: Second Class Upper Division

Courses

Thesis: Experimental and Computational investigation of the antimicrobial activity of isoflavanol from Nigeria propolis.

Awards

Member

Awarded By

America Chemical Society (ACS)

Professional membership in the world's largest scientific society for chemistry.

Member

Awarded By

Royal Society of Chemistry (RSC)

Professional membership in a leading international chemical sciences community.

Member

Awarded By

American Society of Microbiology (ASM)

Professional membership in a premier life science organization dedicated to microbiology.

Class Sportsman of the Year

Awarded By

Department of Microbiology, University of Calabar

Recognized for outstanding sportsmanship and athletic contributions within the Microbiology Department.

Publications

In silico engineering study of selenium (Se) and tellurium (Te) mono-doping and Se-Te co-doping of a covalent organic framework as a sensor for gemfibrozil pharmaceutical pollutants.

Published by

Materials Science and Engineering: B

Summary

Adindu, E. A., Ushie, A. I., Ekpong, B. O., Malu, D. G., Agurokpon, D. C., & Akor, F. O. (2024). In silico engineering study of selenium (Se) and tellurium (Te) mono-doping and Se-Te co-doping of a covalent organic framework as a sensor for gemfibrozil pharmaceutical pollutants. Materials Science and Engineering: B, 310, 117762.

Isolation, Characterization, Antimicrobial Properties, and Theoretical Investigations of a New Isoflavanol from Nigerian Red Propolis for Therapeutic Applications.

Published by

Journal of Molecular Structure

Summary

Iyen, I. S., Anyam, J. V., Malu, D. G., Santali, E., Igoli, J. O., Ekpong, B. O., ... & Tor-Anyiin, T. A. (2024). Isolation, Characterization, Antimicrobial Properties, and Theoretical Investigations of a New Isoflavanol from Nigerian Red Propolis for Therapeutic Applications. Journal of Molecular Structure, 139203.

Transition metals tailoring of phosphorus-doped gallium nitride nanotubes as sensors for N-butenyl homoserine lactone (BHL): A computational study.

Published by

Computational and Theoretical Chemistry

Summary

Ekpong, B. O., Abdullah, H. Y., Emmanuel, E., Benjamin, I., & Agurokpon, D. C. (2024). Transition metals tailoring of phosphorus-doped gallium nitride nanotubes as sensors for N-butenyl homoserine lactone (BHL): A computational study. Computational and Theoretical Chemistry, 114914.

Yttrium-encapsulated fullerene (Y@C80) mono-doping with As, Bi, Sb, and P for the enhanced sensing of methylmalonic acid (MMA) as a biomarker for vitamin B12 deficiency: A DFT study.

Published by

Computational and Theoretical Chemistry

Summary

Ekpong, B. O., Ogbogu, M. N., Edet, H. O., & Emmanuel, E. (2024). Yttrium-encapsulated fullerene (Y@C80) mono-doping with As, Bi, Sb, and P for the enhanced sensing of methylmalonic acid (MMA) as a biomarker for vitamin B12 deficiency: A DFT study. Computational and Theoretical Chemistry, 1242, 114972.

Elucidating the structural basis for the enhanced antifungal activity of amide derivative against Candida albicans: a comprehensive computational investigation.

Published by

In Silico Pharmacology

Summary

Kechi, E. L., Ubah, C. B., Runde, M., Owen, A. E., Godfrey, O. C., Agurokpon, D. C., Odey, M. O., Edet, U. O., Ekpong, B. O., Benjamin, I. & Sampathkumar, G. (2024). Elucidating the structural basis for the enhanced antifungal activity of amide derivative against Candida albicans: a comprehensive computational investigation. In Silico Pharmacology, 12(1), 48.

Structural, electronic characterization, and antiviral potential of a thiadiazol derivative targeting nucleoprotein of Lassa fever virus: insights from DFT investigation, pharmacokinetic, and molecular docking.

Published by

Discover Chemistry

Summary

Ekpong, B.O., Runde, M., Ashishie, P.B. Gulack, A. O., Iyam, S. O., Edet, U. O., Otoh, E. F., Ayoola, O. V., Akor, F. O., Imojara, B., Egbelo, J. E., & Benjamin I. (2024). Structural, electronic characterization, and antiviral potential of a thiadiazol derivative targeting nucleoprotein of Lassa fever virus: insights from DFT investigation, pharmacokinetic, and molecular docking. Discover Chemistry. 1, 18

Comprehensive computational and pharmacokinetic investigation of an amide derivative (C34H34N8O4S2) as a potential drug candidate for tuberculosis: Unraveling structural analysis and reactivity descriptors.

Published by

Journal of the Indian Chemical Society

Summary

Iyam, S. O., Edeghor, U. O., Andrew, B. H., Agurokpon, D. C., Runde, M., Odey, M. O., Akor, F.O., Ekpong, B. O., Eze, A. A., & Benjamin, I. (2024). Comprehensive computational and pharmacokinetic investigation of an amide derivative (C34H34N8O4S2) as a potential drug candidate for tuberculosis: Unraveling structural analysis and reactivity descriptors. Journal of the Indian Chemical Society, 101369.

Surface modification of graphene and fullerene with Sulfur (S), Selenium (Se), and Oxygen (O): DFT Simulation for enhanced zidovudine delivery in HIV treatment.

Published by

BMC chemistry

Summary

Akor, F. O., Edo, G. D., Nelson, F. A., Johnson, A. U., Iyam, S. O., Abubakar, M. N., Gulack, A.O., Ubah, C. B., Ekpong, B. O., & Benjamin*, I. (2024). Surface modification of graphene and fullerene with Sulfur (S), Selenium (Se), and Oxygen (O): DFT Simulation for enhanced zidovudine delivery in HIV treatment. BMC chemistry, 18(1), 156.

Structural analysis, reactivity descriptors (HOMO-LUMO, ELF, NBO), effect of polar (DMSO, EtOH, H2O) solvation, and libido-enhancing potential of resveratrol by molecular docking.

Published by

Chemical Physics Impact

Summary

Adindu, E. A., Godfrey, O. C., Agwupuye, E. I., Ekpong, B. O., Agurokpon, D. C., Ogbodo, S. E., & Louis, H. (2023). Structural analysis, reactivity descriptors (HOMO-LUMO, ELF, NBO), effect of polar (DMSO, EtOH, H2O) solvation, and libido-enhancing potential of resveratrol by molecular docking. Chemical Physics Impact, 7, 100296.

Languages

English

Skills

Scientific Research

APA Citation, MLA Citation, Experimental Design, Data Analysis, Research Methodology.

Computational Chemistry & Drug Discovery

Multiwfn, Chemdraw, Gaussian 16.09W, Gauss view 6.0.16, VMD, DFT Method, Molecular Modeling, Bio-Simulation, Drug Discovery, Biosensor Design, Nanomaterials, Ligand Molecules, Pharmaceutical Applications, Pharmacokinetics (ADMET).

Molecular Biology Techniques

DNA Extraction, Gel Electrophoresis, PCR (Basic), Bioinformatics, Molecular Docking.

Laboratory Diagnostics

Sample Identification, Sample Collection, Sample Handling, Quality Control, Medical Laboratory Procedures, Serological Diagnostics, Hematological Diagnostics, Microbial Diagnostics, Laboratory Training.

Software Proficiency

Microsoft Office, Google Workspace, AutoDock Vina, Biovia Discovery Studio, PyMOL, PyRx, Excel, SPSS, SwissADME, Protox II.